http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-40624-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c0a9bf6cb4633f0e05c048c686e3591 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N33-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N33-10 |
| filingDate | 1974-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-40624-L |
| titleOfInvention | Phenylpropanolamines |
| abstract | 1475913 Phenylpropanolamines BOEHRINGER INGELHEIM GmbH 9 Oct 1974 [11 Oct 1973] 43792/74 Heading C2C Compounds of the general formula (R 1 = H, halogen, CF 3 , OH, C 1-4 alkyl or alkoxy; R 2 = H, C 1-4 alkyl, benzyl) and their salts are prepared by (a) reducing a compound of the formula (R 2 <SP>1</SP> = R 2 , C 1-4 alkanoyl, benzoyl; R 3 =alkoxy, substituted alkoxy) with a complex hydride and, if necessary, deacylating the product, (b) removing the protecting group(s) in a compound of the formula (R 4 = H, protecting group; R 5 = R 1 , OR 7 ; R 6 = R 2 , protecting group; R 7 = protecting group; at least one of M 4,6,7 =protecting group), (c) reducing the corresponding nitropropanol, (d) alkylating or benzylating the primary amine or (e) reducing the corresponding amide, optionally followed by resolution and/or salt formation. The above compounds are sympathicomimetics and increase blood pressure; they may be administered in the form of pharmaceutical preparations containing them in association with a carrier.n[GB1475913A] |
| priorityDate | 1973-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.