http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-40373-L
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-16 |
filingDate | 1973-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1974-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-40373-L |
titleOfInvention | Pyridylalkylamines |
abstract | 1440777 Phenylalkylamines A H ROBINS CO Inc 1 Oct 1973 [2 Oct 1972] 45814/73 Heading C2C Novel compounds of Formula I and acid addition salts wherein Am is amino, di C 1-6 alkylamino, pyrrolidino, piperidino or morpholino R is H, Cl, Br, F, CF 3 or methoxy and n is 1 or 2 excluding the tree base 3-phenyl- 2 - (2 - pyridyl) - N,N - dimethylpropylamine are prepared either by (a) reacting a 2-(#- phenylalkyl)pyridine with formaldehyde and a secondary amine or (b) reducing an α-benzyl-2- pyridylacetonitrile with LiAlH 4 . α - Benzyl - 2 - pyridylacetonitriles are prepared by hydrogenation of α-benzylidene-2-pyridylacetonitriles obtained by reaction of benzaldehydes and 2-pyridylacetonitrile. 2-(#-Phenylalkyl)pyridines are prepared by reaction of 2-picoline with butyl lithium and phenylalkyl chlorides. Pharmaceutical compositions in conventional forms for oral administration having antisecretory activity comprise an above novel compound and a carrier therefor.n[GB1440777A] |
priorityDate | 1972-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.