| abstract |
Phenoxypropylamine derivatives of the general formula: <IMAGE> (I) in which R is a hydrogen atom or a straight-chain or branched alkyl group containing up to 10 carbon atoms, R1 is a hydrogen atom, a straight-chain or branched alkyl group containing up to 10 C atoms or a cyclopentyl, cyclohexyl, benzyl or phenyl group or R and R1 taken together form a pentamethylene-(1,5), tetramethylene-(1,4), 2-azapentamethylene-(1,5), 3-azapentamethylene-(1,5) and 3-oxapentamethylene-(1,5)-group, R2 is an alkyl group containing up to 6 carbon atoms or a benzyl or phenyl group and R3 is a branched alkyl group containing 3 to 6 carbon atoms, a cyanoalkyl group containing up to 6 carbon atoms or a cycloalkyl group containing 3 to 7 carbon atoms, and pharmaceutically-acceptable salts thereof, having a cardio-selective beta -blocking action.n[US4034009A] |