http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-39688-B1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-86
filingDate 1974-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-39688-B1
titleOfInvention New azines and their tautomers, and processes for the preparation thereof
abstract Compounds of the class of 2,2'-azines of 2,4-thiazolidinediones which are substituted in at least one of the 3-positions by allyl, 1-methylallyl, 2-methylallyl or 2-propynyl and in at least one of the 5-positions by hydroxy, and may further contain methyl groups in the remaining 3-position and in the 5-positions, and the corresponding tautomeric 1-[[4-oxo-2-thiazolidinylidene]amino]-5-hydroxy-2-thiohydantoins and 5,5'-dihydroxy-2,2'-dithio-1,1'-bihydantoins have valuable pharmacological properties. In particular, they inhibit the growth of tumours, while their toxicity is low in comparison with their tumour-inhibiting effectiveness. A specific embodiment is the 2,2'-azine of 3-(2-methylallyl)-5-methyl-2,4-thiazolidinedione and of 3-methyl-5-hydroxy-2,4-thiazolidinedione.n[US4697020A]
priorityDate 1973-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 25.