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filingDate 1974-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-39506-B1
titleOfInvention Process for preparing cephalosporins
abstract 1473090 Cephalosporins LILLY INDUSTRIES Ltd 18 July 1974 [19 July 1973] 34337/73 Heading C2C A 7 - α - aminoacetamido - cephalosporin - 4- carboxylic acid is made by reacting a 7-aminocephalosporin-4-carboxylic acid ester with a reactive derivative of an α-aminoacetic acid, in which the amino group is protected by forming an enamine with a #-dicarbonyl compound; removing the amino protecting group from the product; adding sufficient hydrazine or its derivative (e.g. semicarbazide) to prevent reaction of the liberated dicarbonyl compound; and, if desired de-esterifying the resulting 7-α- aminoacetamido compound.n[GB1473090A]
priorityDate 1973-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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