http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-36867-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_571b8abacacea64d3f7089d0983b8b3b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 1972-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-36867-L |
| titleOfInvention | Potentiated antimicrobial compositions |
| abstract | 1405246 Potentiated antibacterial medicines WELLCOME FOUNDATION LTD 4 Aug 1972 [5 Aug 1971 1 Aug 1972] 36774/71 and 35817/72 Heading A5B Antibacterial compositions comprise a competitor of p-aminobenzoic acid or an inhibitor of dihydrofolate reductase, or both, together with a potentiator which is itself a pteridine antagonist (as defined in the specification) and which inhibits the enzyme hydroxymethyldihydropteridine pyrophosphokinase and has a sufficiently low toxicity to a mammalion or arian host. Specified potentiatas are compounds of the formula: wherein R is -alkyl, optionally substituted by a hydroxy group, a halogen atom or by a phenoxy group itself optionally substituted by one or more alkoxy, amino, alkyl or hydroxy groups or halogen atoms and R<SP>1</SP> and R<SP>2</SP> are the same or different and is each alkyl or they form: together a C 4-6 spirocycloalkyl ring system. Specified competitor/inhibitor compounds are various sulphonamides, pyrimethamine, trimethoprim, diaveridine and various derivatives of 2, 4-diamino pyrimidine. The compositions may be put up into conventional forms for oral, parenteral and rectal administration.n[GB1405246A] |
| priorityDate | 1971-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.