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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90
filingDate 1972-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1977-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-36742-B1
titleOfInvention Isoxazolo pyrimidine derivatives
abstract 1374374 Isoxazolopyrimidines and their preparation FMC CORP 13 Oct 1972 [15 Oct 1971] 47240/72 Heading C2C Substituted isoxazolopyrimidines of the formula wherein R and R<SP>1</SP>, which may be the same or different, are straight or branched aliphatic hydrocarbon radicals having 1 to 4 carbon atoms may be obtained by reacting, in an acid medium, a 5-alkyl-3-amino-4-cyanoisoxazole of the formula with an acylating agent containing the radical R<SP>1</SP>-CO-. The acylating agent employed may be an acid chloride or anhydride and a suitable acid is sulphuric acid. The isbxazole starting materials may be obtained by reacting malononitrile with the appropriate trialkyl orthoalkanoate to give the corresponding 2-cyano-3- alkoxy-2-alkenenitrile, hydrolysing the latter to give the 2 - cyano - 3 - hydroxy - 2 - alkenenitrile (which may also be obtained by the reaction of malononitrile with the appropriate acid anhydride in the presence of potassium carbonate), treating the free hydroxy compound with PCl 5 to give the corresponding 3-chloro-2-cyano-2- alkenenitrile, and reacting the latter with N- hydroxyurea (prepared by the reaction of hy. droxylamine hydrochloride with ethyl carbamate in the presence of sodium hydroxide). The products possess herbicidal properties and may be formulated and applied in a conventional manner.n[GB1374374A]
priorityDate 1971-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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