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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
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filingDate 1972-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1972-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-36265-L
titleOfInvention 1,4-dihydropyridinedicarboxylic acid esters
abstract 1358951 Esters BAYER AG 10 April 1972 [10 April 1971 5 Nov 1971] 16462/72 Heading C2C Compounds of the general formula (R = Ph substituted by at least one NO 2 , CN, N 3 , S alkyl, SO alkyl or SO 2 alkylgroup and optionally by one or more alkyl or alkoxy groups or halogen atoms, the total number of substituents being not more than three, or naphthyl, quinolyl, isoquinolyl, pyridyl, pyrimidyl, thenyl, furyl or pyrryl optionally substituted by one or more alkyl or alkoxy groups or halogen atoms; R<SP>1</SP>.<SP>3</SP> = H, alkyl; R<SP>2</SP>.<SP>4</SP> = different acyclic or cyclic, saturated or unsaturated, hydrocarbon groups, the carbon chain being optionlly interrupted by one or two oxygen atoms and/or substituted by an OH group) are prepared by reacting RCH =C(COR<SP>1</SP>)COOR<SP>2</SP> with R<SP>3</SP>C(NH 2 ) = CHCOOR<SP>4</SP> or with R<SP>3</SP>COCH 2 COOR<SP>4</SP> and ammonia. These compounds are coronary dilators, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.n[GB1358951A]
priorityDate 1971-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 25.