http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-35323-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 |
filingDate | 1971-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-35323-B1 |
titleOfInvention | Tropane-3-ol derivatives and processes for their preparation |
abstract | 1351526 α-Phenyl-cyclopentane acetic acidnortropine esters BOEHRINGER INGELHEIM GmbH 28 May 1971 [1 June 1970] 17926/71 Heading C2C Novel ester of the Formula I wherein R 1 is hydrogen or halogen or C 1-4 alkyl or alkoxy, R 2 is hydrogen, C 1-5 alkyl, C 3-6 cycloalkyl with the proviso that where R 1 is hydrogen and R 2 is methyl the α-phenyl-cyclopentane acetoxy moiety is # to the tropine moiety and acid addition and quaternary ammonium salts thereof may be prepared either by reacting a compound II where R 2 is other than hydrogen with an organic acid derivative III wherein Y is halogen, C 1-4 alkoxy or another group removable as an anion and if desired dealkylating the N-alkyl compound produced to give R 2 = H or by N-alkylating a compound I in which R 2 is hydrogen. Pharmaceutical compositions of I show anticholinergic activity when administered orally, parenterally or rectally with the usual excipients.n[GB1351526A] |
priorityDate | 1970-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.