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filingDate 1970-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1972-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-35304-L
titleOfInvention 3-propionylsalicyclic acid
abstract 1343118 Propionylsalicylic acid RECORDATI SA CHEMICAL & PHARMACEUTICAL CO 27 Oct 1970 [1 Aug 1970] 50978/70 Heading C2C The invention comprises 3-propionylsalicylic acid. The compound is prepared by isomerizing 2-hydroxy-3-allylpropiophenone to 2-hydroxy- 3-propenylpropionphenone, oxidizing this with ozone in a reaction medium consisting of a mixture of formic and acetic acids to give 3- propionylsalicylic aldehyde which is subjected to alkaline fusion to give 3-propionylsalicylic acid. The acid may be converted to an ester of 3-methylflavone-8-carboxylic acid with an aminoalcohol by first esterifying the acid with a C 1-4 alkanol, reacting the product with sodium benzoate and benzoyl chloride at 180-190‹ C. to give a C 1-4 alkyl ester of 3-methylflavone-8- carboxylic acid and either transesterifying this ester with an aminoalcohol or hydrolysing the alkyl ester and esterifying the free acid with an aminoalcohol.n[GB1343118A]
priorityDate 1970-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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