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filingDate 1970-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1975-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-35203-B1
titleOfInvention Steroid-containing pharmaceutical preparations
abstract 1317184 Injectable anaesthetics GLAXO LABORATORIES Ltd 11 June 1970 [20 June 1969] 31371/69 Heading A5B [Also in Division C2] Anaesthetic compositions suitable for use by parenteral administration comprise an aqueous solution containing at least 1mg/ml of 3α- hydroxy-5α-pregnane-11, 20-dione and a non- ionic surface-active agent serving to solubilize the steroid. Preferably they contain at least 1% by weight of the agent and this has an HLB value of 9-18. Suitable agents include polyoxyethylated derivatives of fatty glyceride oils, polyoxyethylene ethers of long-chain alcohols, polyoxyethylene - polyoxypropylene ethers, polyoxyethylene ethers of alkyl phenols, polyoxyethylated fatty acid esters of sugar alcohol anhydrides, long-chain alkanoyl mono- and di-alkanolamides and polyethylene glycol esters of long-chain fatty acids. The solubility of the anaesthetic steroid may be further increased by addition of a steroid of the formula: wherein R is an optionally substituted alkanoyl, aroyl or aralkanoyl group. These steroids are described and claimed in Specification 1317185. They also possess some anaesthetic activity.n[GB1317184A]
priorityDate 1969-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 24.