http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-32565-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
filingDate | 1968-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1973-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-32565-B1 |
titleOfInvention | New cyclopeptides |
abstract | (A) Cmpds. (I):- R-Cyclopeptide A where cyclopeptide A is probably where MePro = L-trans-4-methylproline MeThr = L-N-methylthreonine MeVal = L-N-methylvaline MeLeu = L-N-methylleucine Pro = L-proline Glyc = glycocol Leu = L-leucine and Thr = L-threonine and R = H, alkanoyl, alkenoyl, alkadienoyl, CO2 alkyl, aroyl, aralkanoyl, S-aryl, SO-aryl, SO2-aryl, CO-cycloalkyl, CO-heterocyclyl, heterocyclylalkanoyl, or the residue of a linear or cyclic peptide bonded via = O to the N atom of the L-trans-4-methylproline side chain of A. Alkyl residues etc. may have up to 50 C atoms and is opt. subst. by one or more Hal, NH2 and/or (1-5C) S alkyl gps., aromatic gps. are Ph or naphthyl residues opt. subst. by one or more alkyl, PhCH2, NH2, Nalkyl2, and/or NO2; heterocyclic residues may be mono- or polynuclear, and may contain one or more N, S and/or O atoms and be opt. subst. by one or more alkyl and/or NO2, peptide residues may contain 2-15 aminoacids; NH and NH2 substits. may be substd. by one or more (1-30C) alkyl, alkanoyl, aralkyl, CO2 alkyl, and/or CO2 aralkyl. (B) Acid addn. salts of (I). (C) Quaternary ammonium salts of (I). Anti-biotics (broad spectrum) and esp. anti-tuberculosis.n[DE1805280B2] |
priorityDate | 1967-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.