http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-32238-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1f93c519830946d79a486d9c90be46c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 |
| filingDate | 1968-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-32238-L |
| titleOfInvention | Water-soluble salts of ampicillin |
| abstract | Method for water-soluble salts (I) of D(-)-alpha-aminobenzyl penicillins (II), wherein II (as hydrate or anhydrous form) are suspended in a suitable solvent (e.g. EtOH, DMF, or pref. CH2Cl2), and a primary (III), sec. (IV), or cyclic (V) amine is added until the penicillin goes into solution. This requires 3-4 mols III, 1.16 mol IV or 2.47-5.0 mols. V/mol hydrated II. The solution is dried e.G. with CaCl2 or Na2SO4, and filtered at 8-12 deg., and may be freeze-dried or evapd. in vac. to give the amine salt of II, or treated with an alkali salt, e.g. NaOMe, KI, NaSCN, or a carboxylate in order to precipitate the alkali metal salt. Exact conditions depend on the cpd. being prepared. Broad spectrum antibiotics.n[CH535787A] |
| priorityDate | 1967-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.