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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B60K2006-268
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-50
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filingDate 1968-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1968-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-31945-L
titleOfInvention Carbamates of pyridine-methanol
abstract 1,200,199. Hydroxymethylpyridine carbamates. T. SHIMAMOTO, M. ISHIKAWA, H. ISHIKAWA, M. INOLLE, and T. SHIMAMOTO. 26 Oct., 1967 [16 Feb., 1967; 17 April, 1967], No. 48795/67. Heading C2C. Novel hydroxymethylpyridine carbamates of the formula wherein R 1 and R 2 each represent H 1 alkyl, phenyl or benzyl, or R 1 and R 2 together form a divalent radical; R 3 is alkyl, OH, alkoxy, NH 2 , alkylamino, or dialkylamino, and the group -CH 2 O.CO.N(R 1 )R 2 is in the 2- or 6- position are prepared by reacting the corresponding 2- or 6-aryloxycarbonyloxymethylpyridine derivative with ammonia or an amine of the formula HN(R 1 )R 2 , or, for compounds of the above general formula in which R 1 is hydrogen and R 2 is alkyl, phenyl or benzyl, by reacting the appropriate 2- or 6-hydroxymethylpyridine with an alkyl phenyl or benzyl isocyanate or with compounds which can be converted to such an isocyanate under the reaction conditions, with, if necessary, a catalyst to promote such conversions. 2 - Phenoxycarbonyloxymethyl - 5 - ethoxycarbonylpyridine and 2 - (p - bromophenoxycarbonyloxy) - methyl - 5 - ethoxycarbonylpyridine are made by reacting 2-hydroxymethylpyridine with phenyl chloroformate and p-bromophenyl chloroformate respectively. Therapeutic compositions, having anti-inflammatory activity and suitable for oral administration, contain the above novel carbamates as the active ingredients and pharmaceutically acceptable carrier or diluents.n[GB1200199A]
priorityDate 1967-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 39.