http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-20001034-A1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337
filingDate 2000-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1a5d40e7ea78fa8749574209493aeb7
publicationDate 2002-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-20001034-A1
titleOfInvention A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt
abstract A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt includes the addition of extra methyl tert-butyl ether to the reaction mixture to supersaturate the crystallisation matrix. A seed slurry is made up in a make-up/delivery vessel and delivered, under pressure, to the reaction mixture. The process produces crystalline atorvastatin calcium within a consistent size range on a factory scale.
priorityDate 1999-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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