| abstract |
A subject-matter of the invention are (phenylmethylene)-2-(alkyl)-1-[ω-(amino)-alkoxyimino]-cycloalkane derivatives of general formulan n whereinn R represents hydrogen, C₁₋₄ alkyl or hydroxyl, R₁ stands for C₁₋₁₂ alkyl, R₂ and R₃ independently each represents hydrogen, a C₁₋₁₂ alkyl group, optionally substituted by hydroxy, or a C₂₋₁₂ alkenyl group, nor R₂ and R₃ together with the nitrogen atom to which they are attached form a 4- to 7-membered heterocyclic ring, optionally comprising an oxygen, sulfur or a further nitrogen atom, which latter optionally may carry a phenyl, benzyl or C₁₋₄ alkyl substituent, R₄ and R₅ independently each stands for hydrogen, halogen or a C₁₋₄ alkoxy group, or together represent a 3,4-methylenedioxy group, n is an integer from 2 to 5 nand A represents a valency bond or a -CH₂-group, as well as stereo and optically active isomers and their mixtures, acid-addition salts and quaternary ammonium derivatives thereof.n Furthermore the invention is concerned with a process for preparing these compounds as well as medicaments containing them and the use of them for preparing medicaments, particularly having ulcus and gastric-acid-secretion inhibiting effects. |