abstract |
New amino acid derivatives of the formula I. R¹-C p H 2p - (NH) q -CO-NH-CHR 2 -CO-ZC m H 2m -CHWR 3 -CO-NH-CHR 3 -CR⁴- (CHR⁵) n -CO-EQY I wherein R¹ to R⁵, p, q, Z, m, n, E, Q, W and Y have the meanings given in claim 1, and their salts inhibit the activity of human plasma renin. |