| abstract |
Enol esters and ether prodrugs of 3-acyl-oxindole-1-carboxa mides of formulae (I) are new, where X and Y=H, Fluoro or chloro R1=2-thienyl or benzyl R=2-10C alkanoyl, 5-7C cycloalkylcarbonyl, 7-10C phenylalkanoyl, chlorobenzoyl, methoxybenzoyl, thenoyl, omega-1-3C alkoxycarbonyl 3-5Calkanoyl, 2-10C alkoxycarbonyl, phenoxycarbonyl, 1-(2-4C acyloxy) 1-4C a lkyl, 1-(2-5C alkoxycarbonyloxy) 1-4C alkyl, 1-3C aulponyl, methylphenylsulponyl and di 1-3C alkylphosphonate. |