http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-T55989-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 |
| filingDate | 1990-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1af07a1b6adb8fefd828858218041bf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6693729e3c46fc22e52c20f06b6bc026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8279ce11c4fb389bdb96a8667d01361d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15b16bf0b25af68e35b4e1a029b4edbf |
| publicationDate | 1991-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-T55989-A |
| titleOfInvention | Process for producing pharmaceutical compositions containing n-imidazolyl derivatives of bicyclic compounds in a given case with cyclosporins |
| abstract | The invention relates to the use of N-imidazolyl derivatives of bicyclic compounds of general formula (I), wherein (a) compound alpha is (II) wherein Y completes a single bond or is oxygen or a -CH2- group and the symbol --- represents a single or double bond or (b) compound alpha is (III) and the symbol --- represents a double bond; one of R1, R2, R3 and R4 is -CH2OH, C2-C4 acyl, (IV), -COOR7, -CH2COOR7, (V), (VI) or (VII) in which each of R7, R8 and R9 is independently hydrogen or C1-C4 alkyl, and the others are independently chosen from hydrogen, hydroxy, halogen, C1-C4 alkyl, C1-C4 alkoxy and -COOR7 wherein R7 is as defined above; and one of R5 and R6 is hydrogen and the other is hydrogen, C1-C6 alkyl or phenyl; or a pharmaceutically acceptable salt thereof, in particular in combination with cyclosporin A. The compounds obtained are useful in preventing and/or treating cyclosporin A-induced nephrosis in mammals. |
| priorityDate | 1989-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.