http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-T41044-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-24
filingDate 1984-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4a51eb3bc117d27694290a0ccde26b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beefe84a0c5b5cdd5e07b3110a160800
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_294fe479e9e6567ba145ff7173f0742c
publicationDate 1987-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-T41044-A
titleOfInvention Improved process for preparing 4-demethoxy-daunorubicin
abstract 4-Demethoxy daunorubicin of formula (I) is made from optically-active 4-demethoxy daunomycinone, which is condensed in organic solvent in presence of silver trifluoromethanosulphonate, with a N,O-trifluoroacetyl-protected 1-chloro daunosamine, to obtain the N,O-protected alpha-anomeric glucoside. By elimination of the protective gps., first with methanol and then by mild alkaline hydrolysis, e.g. with dil. aq. NaOH soln., the free glucoside base (I) is obtd., which is isolated as the hydrochloride.
priorityDate 1984-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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