| abstract |
BACKGROUND OF THE INVENTION The present invention relates to tricyclic non-peptide vasopressin antagonist antagonist compounds, to their use, to processes for their preparation and to pharmaceutical compositions containing them. In the general formula (I) of the present invention, R is -OH, -NR 1 R 3, -NHOR 1, -NH- (CH 2) -COOH, R 1 and R 2 independently of one another may be hydrogen or lower alkyl, R3 is X is CH2, NR1, oxygen or sulfur atom, p is 1-4, q is an integer from 2 to 4, R4 and R5 independently of one another are hydrogen, lower alkyl, halogen, cyano, trifluoromethyl, amino, hydroxy or lower alkoxy, R6 lily of the valley; Ar is a leash of the formula or. (I) ŕ |