http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-9903968-A2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-89 |
| filingDate | 1997-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_352df6d71996ddd19c96f4799ccd8f70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1014cb73de818b09af031a19af3e6ab3 |
| publicationDate | 2000-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-9903968-A2 |
| titleOfInvention | Non-peptide bombesin receptor antagonists and their use |
| abstract | The present invention relates to compounds of the general formula (I) in which Ar is a substituted phenyl or pyridyl ring; R 1 is hydrogen, straight or branched alkyl or cyclic alkyl; R8 is hydrogen or a ring with R1; R2 is a hydrogen atom, in the case of a straight or branched chain alkyl or cycloalkyl ring containing one or two xenogeneic or nitrogens; R 9 forms a ring containing a hydrogen atom or R 2, in a given case, containing a xenogene or a nitrogen moiety; Ar1 is an ancestor of Ar, and pyridyl N-oxide, indolyl, imidazolyl and pyridyl; R 4, R 5, R 6 and R 7 are hydrogen or methyl; R3 is an aryl of Ar, and a hydrogen atom, a hydroxy, a dimethylamine, a N-methylpyrilyl, an imidazolyl, a tetrazolyl, a thiazole, a thiol, a phenyl or pyridylpyrrolidone, cyclodexyl, 2,2-dimethyl-1,3-dioxoanil. , 2,2-bis-trifluoro-methyl) -1,3-dioxoanil), or (a) a tubular coat of the general formula. The invention also provides pharmaceutically acceptable salts of the compounds. The compounds of the present invention antagonize the skin lesions, which can be used to treat or prevent a variety of disorders including depression, psychosis, periodic affective disorders, cancer, nutrition disorders, gastrointestinal disorders, including colitis, Cröhn's disease, and obstructive bowel disease, sleep disorders, and memory loss. ŕ |
| priorityDate | 1997-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 277.