abstract |
The present invention relates to compounds having the general formula (I), wherein the bond is optionally double bonded; It stands for Nitrogen Nitrogen or CR7 Tube; B is -NR1R2-, -CR1R2R10-, -C (= CR2R11) R1-, -NHCR1R1R10-, -OCR1R2R10-, -SCR1R2R10-, -CR2R10NHR1-, -CR2R10OR1-, -CR2R10SR1-, or -COR2 tube; J and K are independently selected from the group consisting of nitrogen and carbon; and J and K are each not a nitrogen atom, D and E are independently nitrogen, sulfur, or oxygen or CR 4, C = O, C = S, CR 4 R 6 or NR 8; G is nitrogen or carbon; the invention further relates to the use of these compounds for the prevention or inhibition of a follicular disorder which can be treated by CRFantagonization. ŕ |