| abstract |
The present invention relates to a pharmaceutical composition for increasing the capacity of the sphincter, which is a compound of the general formula (I) in which R1 and R3 are independently hydrogen, -CH3, -C (= O) - (C1-C6) -alkyl or (= O) -Ar, from which Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamethylene imine and piperidine radical substitutes, as well as pharmaceutically acceptable salts or solvates thereof. The present invention further relates to an urinary retention or defecation disorder, or a reflux disease of the esophagus, or a symptom thereof, which comprises an effective amount of a compound of general formula (I). ŕ |