http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-9902536-A2
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D335-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-66 |
filingDate | 1996-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_410f993bcc6c9916d530d0d96484820c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3776eeb6409a4c24d5bd91c48ccb77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c33c7c7936022b5c9613afc52bb0c56 |
publicationDate | 1999-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HU-9902536-A2 |
titleOfInvention | Tetrahydronaphthalene, chromane, thiochroman, and 1,2,3,4-tetrahydroquinoline carboxylic acid retinoid-like aryl or heteroaryl amides |
abstract | The present invention relates to novel compounds of general formula (I) for retinal-like biochemical activity in which X is S, O, NR ', from which R' is a hydrogen atom or a C 1-6 alkyl radical, or X is [C (R 1) 2] n. wherein n is an integer from 0 to 2; Y is a phenyl or naphthylpyrrolid, or the next heterocycle; W is a substituent retaining the following: F, Br, Cl, I, C 1-6 alkylthioalkyl, C 1 -C 6 alkyl substituted with pendulum moiety, NO 2, N 3, OH, OCH 2 OCH 3, O- (C 1 -C 10 alkyl), tetrazine, CN, SO2 (1-6 Carbon Black), SO2 (Cylindrical Carbons 1-6 substituted with cylindrical earth), SO- (C 1-6 Carbon alkyl), CO- (C 1-6 Carbalkyl), COOR 8, Phenyl, substituted phenyl tube with W W is not a dowel or a substituted phenyl tube; L is - (C = Z) -NH-, or -NH- (C = Z) -; Z is O or S; A is (CH2) q, where the parameter value q is 0-5, C3-6 straight or branched Carbon alkyl, C3-6 cyclic alkyl, 2 to 6 carbon atoms and 1 or 2 double bond alkenyl tubes, 2 to 6 carbon atoms 0 and 1 or 2 triple-bonded alkynyl powder, B is -COOH or a pharmaceutically-prodrug thereof, COOR8, CONR9R10, -CH2OH, CH2OHR11, CH2OCOR11, CHO, CH (OR12) 2, CHOR13O, -COR7, CR7 (OR12) 2, CR7OR13O, wherein The meaning of R1, R13, and more, the p, m, n, r parameter values are predetermined as defined in claim 1. ŕ |
priorityDate | 1996-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 434.