http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-9902470-A2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
| filingDate | 1997-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e4f5d2291f662ec0f8f474f13b0d9ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd645e9291ff0c988b5b62a2747193e0 |
| publicationDate | 1999-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-9902470-A2 |
| titleOfInvention | Biphenylsulfonylaminoalkylcarboxylic acid derivatives and pharmaceutical compositions containing them |
| abstract | The present invention relates to compounds of general formula (I) and pharmaceutical compositions containing them. In the general formula (I), R 1 is C 1-6 alkylthiourophenyl, halo, nitro, (CH 2) 0-4 -NR 4 R 5, cyano, OR 4, CH = O, CF 3, CNR 4 R 5 = O and COOR 4; R2 is a hydrogen atom or a C 1-6 alkyl radical, in which case it may be substituted with the following tuber, phenyl, substituted phenyl, phenoxy, substituted phenoxy, NR 4 R 5, OR 6, carboxy, carboxy, H 2 N-C = NH-HN-, tertiary, methylthio, indium, imidazole, and phthalimide; R 3 is a hydrofluoric acid coat, O- (C 1-6 alkyl) -, or NHOH; R4 is a hydrogen atom, a C 1-6 alkyl or a C 1-6 alkanol; R 5 is a hydrogen atom or a C 1-6 alkyl radical; and R 6 is a hydrogen atom, C 1-6 alkyl, C 1-6 alkenyl, phenyl, or substituted phenylthio. The compounds of the present invention have matrix metalloproteinase enzyme inhibitory activity, for example, in the treatment of cough-induced diseases such as arthritis, atherosclerosis, rheumatoid arthritis and duodenal ulcer. ŕ |
| priorityDate | 1997-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.