| abstract |
The present invention relates to compounds of formula (II) wherein the substituents have the following meanings: R1 and R6 are independently hydrogen, C1-C6alkyl, trifluoromethyl, cyano, C1-C6alkoxy or halogen; R 2 is hydrogen or C 1-6 trialkylsilyl; R 3 is hydrogen or C 1-6 alkoxycarbonyl; R 4 and R 5 are each independently hydrogen or C 1-6 alkyl; R7 and R8 are independently OR9 or NR10R11; R 9 is hydrogen, C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl, C 1 -C 12 silylalkyl, aryl, arylalkyl, alkoxyalkyl, or heteroaryl; R 10 and R 11 are each independently hydrogen, C 1 -C 12 alkyl, arylalkyl, aryl, furanylalkyl or alkoxycarbonylalkyl; R 12 and R 13 are each independently hydrogen, C 1 -C 12 alkyl, aryl or aralkyl. The compounds of the invention are useful in the preparation of antidiabetic, antihyperglycaemic and antiobesity medicaments. HE |