| abstract |
The present invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein X is -NRt, -S (O) g- or oxygen; R 1 is hydrogen, optionally substituted with one or more C 1-6 alkyl alkyl moieties or OH or CN moieties; or R1 is - (CH2) h-aryl, -COR1-1, -COOR1-2, -CO- (CH2) h-COR1-1, C 1-6 alkylsulphonyl, -SO2- (CH2) h-aryl or - (CO) j-Het; R 2 is hydrogen, C 1-6 alkyl, - (CH 2) h -aryl, or fish; R3 and R4 are homogeneous or different and are hydrogen or fish; R5 is hydrogen, C1-C12 alkyl, C3-12 cycloalkyl, or C1-6 alkoxy substituted with one or more fish genes. The invention also relates to antimicrobial pharmaceutical compositions containing the compounds of general formula (I). ŕ |