| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 |
| filingDate |
1997-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_594c45889f05351cb6dda10bb9f170a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9797024b8d5785994157291697bc214f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b1a1977a84d3bbb16f1606f7690001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9329f21594d0d46b5069d5c4a2d1f86d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46b6583c10451cf556be8c7232f107e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72b80ebb09a7d49dd1616d9da03c68d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c48995861ea8f9ebecf58e820f13bdb |
| publicationDate |
1999-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-9900574-A2 |
| titleOfInvention |
Thrombin Muteins as Thrombin Inhibitors Antibodies |
| abstract |
Trombin surgeries that have the following sequence differences from natural trombin: a) replacement of a Gly with Ala, in which Gly is located in the Tyr-Gly-Phe sequence environment and occupies position 558 in the natural hymen prothrombin; b) replacement or deletion of at least one of the following residues: b1) His, which is located in the Ala-His-Cys sequence environment and occupies position 363 in the natural hymen trombin; b2) Asp, which is located in the Arg-Asp-Ile sequence environment and at position 419 in the naturally occurring trombin (SEQ ID NO: 14); b3) Ser, which is located in the Asp-Ser-Gly sequence environment and occupies position 525 in a natural hymen prothrombin; use of these as antidotes. ŕ |
| priorityDate |
1996-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |