abstract |
FIELD OF THE INVENTION The present invention relates to novel compounds of the general formula (I), b 3 agonists and pharmacological eye-catching salts. In any case, R1 is hydrogen or halogen; R2 is a hydrogen atom, a hydroxyxyl, a alkyloxy, a mono or double-substituted alkyloxycarbonyl or carboxylic acid, substituted alkyl radical, substituted with an alkylamine carbamyl tube, which may be substituted by an alkylamine carbamyl tube on an alkyloxy, C4-6 cyclic cyclic amine ring. -completely substituted with corticol, alkyloxycarbonyl or carboxy; R3 is hydrogen, hydroxyl, alkyloxy, mono- or polysubstituted xyloxy or carboxy; or R2 and R3 are taken together to form a carboxyethyl or alkyloxycarbonylpyrrhene-substituted methylene dioxy tuber; m and n are 0 or 1, and their pharmacologically evacuated salts. The compounds of the present invention have pentral adrenergic β 3 stimuli and are highly selective for the β 3 adrenergic receptor. The present invention also relates to a process for the preparation of the compounds, to intermediates used in the process, and to pharmaceutical compositions containing avers. ŕ |