| abstract |
In order to stabilize the solid and bulk formulations of cilansetron or acid addition salt thereof of the present invention as active ingredient, sufficient amount of a water-soluble acidic additive is selected from the group consisting of: acids, the acidic salts of the above-mentioned multi-basic organic acids; Further, the present invention is directed to the use of the above acidic additives for the stabilization of cilansetron in pharmaceutical compositions against racemization. ŕ |