http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-9701364-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c3475fe8e01e5b9361367733b93030 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 |
| filingDate | 1997-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db2d89d81a25288729a027401a6a8381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bc58e560f89e2e99d481530a7b1d532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c531539826bba6e2bbbb2b969bf3cee8 |
| publicationDate | 1999-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-9701364-A2 |
| titleOfInvention | Process for the Preparation of (R) - and (S) -isomers of {1-methyl-2- [3- (trifluoromethyl) phenyl] ethyl} and the isomers and their salts |
| abstract | The present invention relates to a process for the preparation of (R) - and (S) - {1-methyl-2- [3- (trifluoromethyl) phenyl] ethyl} amine of formula (I), of which the (S) -isomer an intermediate for the preparation of dexphenfluramine, from which a) (R) - or (S) -α-methylbenzylamine of formula (II) of formula (III) is prepared according to a) under stereospecific reductive amination conditions ) -phenyl] -2-propane (R), (R) - or (S), (S) -N- (1-phenylethyl) - (1-methyl-2-3- ( trifluoromethylphenyl) amine diastereomer and b) debenzylating the compound of formula (IV) or an organic or inorganic acid salt thereof under reductive conditions. The intermediates of formula (IV) and their salts with organic or inorganic acids are also part of the invention. ŕ |
| priorityDate | 1997-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.