| abstract |
The present invention relates to compounds of general formula (I) for use in the treatment of central nervous system disorders in the preparation of an ointment. In the general formula (I), Z is a (b), (c), (d) or (e) anthers, R1 is a hydrogen atom, an amino, an alkylamino, a dialkylamino, an alkyl anthem, a fish antigen or trifluromethyl methyl tern, R2 hydrogen atom or alkyl tern, R3 hydrogen atom, amino, alkylamino, dialkylamino, alkyl, trifluoromethyl, alkoxyalkyl, or halogen atom, R4 amino, alkylamino dialkylamino, alkyl, alkoxyalkyl or halogen atom, R5 hydrogen atom, alkylamino, alkylamino, alkoxyalkyl or halogen atom, R6 alkyl, alkylamino, alkylamino, halogenated R7 is amino, alkylamino, dialkylamino, alkoxy, alkylsulfanyl, mercapto, pyrrolidin-1-yl or azetidin-1-yl, R8 amino, alkylamino, dialkylamino, benzylamino, alkoxy, alkylsulfanyl, halogen, pyrrolidin-1-yl or azetidin-1-yl, R9 and R10 alkoxy or alkylamino R11 is hydrogen or fish, R12 is hydrogen or alkyl, and optionally is a double bond, provided that at least one of R7 and R8 is other than mica. The present invention also relates to novel compounds of the general formula (I), their preparation and pharmaceutical compositions containing them. Compounds suitable for treating or preventing central nervous system disorders ŕ |