http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-9700591-A1

Outgoing Links

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filingDate 1997-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7528b8b3d287febc48223c1851a3aa
publicationDate 2000-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-9700591-A1
titleOfInvention Use of naphthalene derivatives for the treatment of lung carcinoma
abstract The present invention relates to the use of compounds of formula (I) in the manufacture of a medicament for inhibiting cell growth in squamous cell lung carcinoma. In the general formula (I), R1 is a 5-7 membered heterocyclic tube having an optionally substituted, saturated or partially unsaturated 1-2N atom at the N-atom, R2 is -R4, -OR-R4, -OS (O) 2-R4, -NR4R5, R4- (CH2) b-NH (C = X) - (CH2) c-, R4- (CH2) bO (C = O) NH- (CH2) c- (C = O) NH-, R4 - (C = O) NH- (C = O) NH-, - (CH2) b-NH (C = X) - (CH2) c-R4, R4- (CH2) bO (C = O) - (CH2 ) c-, - (CH2) bO (C = O) - (CH2) c-R4, -NH (C = X) NH-R4, R4-O (C = O) O-, -O (C = O ) NH-R4, R4-O (C = O) NH-, - (CH2) b- (C = O) - (CH2) c-R4, -NH-S (O) 2-R4, -C (OH ) R4R5, -CH (OH) -R4, - (C = O) -NR4R5, -CN, -NO2, R4- (CR6R7) fO- (CR8R9) g-, alkyl-substituted alkyl, powdered, unsubstituted or unsubstituted alkenyl- or alkenylalkenyl- R3 is a port at any carbon atom of the naphthalene ring capable of forming a further bond, R4 and R5 are each independently a 5-6 membered, optionally substituted and optionally decensated heteroaromatic ring, hydrogen atom, C F3, alkyl or alkylaryl, R6 and R7 are independently hydrogen or alkyl, R8 and R9 are independently hydrogen or, optionally, fluorine-substituted alkyl, 0 and 2, 1 and 2, 3, 4,5 or 6, so b + c is at most 6, f is 0, 1, 2, 3, 4,5 or 6, g is 0, 1, 2 or 3. ŕ
priorityDate 1996-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 39.