| abstract |
The present invention relates to a compound or a pharmaceutically acceptable salt thereof having the general formula (I) wherein R 1 is hydrogen, hydroxy tube, C 1-4 alkoxy, C 1 -C 6 alkyl, or -OSO 2 (C 6 -C 6 alkyl). anthrax, R2 represents a hydrogen atom, a hydroxylic anhydride, a C1-C4 alkoxy, a -OOC6H5, -OCO (C1-C6 alkyl) or -OSO2 (a 2-6 carbonyl alkyl) or halogen atom, R3 represents a 1-piperidinyl, -1-pyrrolidinyl, dimethyl-1-pyrrolidine, 4-morpholine, dimethylamino, diethylamino, diisopropylamine or 1-hexamethyleneimine, and n is 2 or 3. The ( I) a compound of the general formula as an active ingredient for the treatment of the symptoms of post-menopausal swelling syndrome, including predominantly stenosis, cardiovascular disease, hyperlipidemia or thermo-dependent r and moreover, it is used to inhibit the proliferation of cells of the aortas smoothis and resterosis. ŕ |