| abstract |
The present invention relates to inclusion complexes of aryl heterocyclic salts. The composition according to the invention comprises an aryl heterocyclic compound, for example, a pharmaceutically acceptable salt thereof in cyclodextrin of ziprasidone. Preferred cyclodextrin is SBECD and HPBCD. The composition may also comprise a dry mixture, a dry inclusion complex or an aqueous solution. Preferably, the salt / cyclodextrin closure complex provides at least 2.5 mgA / ml of zipras when the complex is dissolved in 40% w / v water. Various ziprasidone salts are preferred, including mesylate, ezylate, besylate, tartrate, napsilate and azosylate. ŕ |