http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-222248-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4180fc57a693864e2ce2dbfd64a9278 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0806 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 1994-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e5be9be5926630b50dbac45980c19c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f303fa873f06f9caeae89dace2a3d14 |
| publicationDate | 2003-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-222248-B1 |
| titleOfInvention | Thrombosis (aza-cycloalkyl) alkanoyl peptides, pseudopeptides, and pharmaceutical compositions containing these compounds |
| abstract | The present invention relates to antithrombotic compounds, and more particularly to (azacycloalkyl) alkanoyl peptides and pseudopeptides of formula (I) which inhibit platelet aggregation and thrombus formation in mammals. These compounds are useful in the prevention and treatment of thrombosis associated with pathological conditions such as myocardial infarction, chills, peripheral arterial disease, and diffuse intravascular coagulation. In the general formula (I) of the compounds of the present invention, B is a C1-7 alkyl group, Z is a group of formula (a) wherein F is a C1-7 alkyl group, a C3-9 cycloalkyl group and a C1-4 alkyl group. , adamantyl (C 1-4 alkyl), (C 3-8 cycloalkyl) - (C 3-8 cycloalkyl) - (C 1-4 alkyl), C 3-8 cycloalkyl, (C 8-12 bicycloalkyl) - (C 1 -C 4 alkyl), phenyl (C 1 -C 4 alkyl), naphthyl (C 1 -C 4 alkyl) or tetrahydronaphthyl (C 1 -C 4 alkyl), G is OR 1 or NR 1 R 2 - wherein R 1 and R 2 are hydrogen or independently C 1-4 alkyl optionally substituted with adamantyl, r is 0 or 1, m is 2, 3 or 4, n is 1, 2, 3, 4, 5 or 6, and p is 1. The compounds of formula (I) are pharmaceutically acceptable salts as well as pharmaceutical preparations containing all these compounds as active ingredients. ŕ |
| priorityDate | 1993-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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