http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-222018-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24bfe4544f7080a127c51d94c333199a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-04 |
| filingDate | 1997-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ee084e671586d84e694a18727d7fc35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fee7567733a04a9adeca1af07c3bf80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffe630415bbefa436d48793627698f9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ed4ef8c460da6939b40bb8613898174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f2c224db52e6358e9a497f3d2a42f30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2c1b2fa82f3015fdf47915597569ac9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a132278f0605365e26d90f79f4f37014 |
| publicationDate | 2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-222018-B1 |
| titleOfInvention | Resolution procedure for the preparation of (-) - trans and (+) - trans isomers of chrysanthemic acid |
| abstract | During the resolution process, solid alkali metal hydroxide and methanol were added to trans-chrysanthemic acid or a mixture of trans-chrysanthemic acid and cis-chrysanthemic acid, followed by D- (-) - threo-1- (4-nitrophenyl) -2- (dimethyl) amino) -1,3-propanediol is added, the precipitated diastereomeric salt is recovered and the (+) - trans-chrysanthemic acid is liberated from it and, if desired, the chrysanthemic acid isomeric mixture, as is known in the mother liquor, is recovered in optically pure (-) - trans-chrysanthemic acid and separating the remainder of the racemic moiety using the fentanyl melting agent in ethyl acetate, or reacting with 0.2 to 0.8 equivalents of achiral base, preferably sodium hydroxide or benzylamine, and breaking the resulting mixture into fractions of higher optical purity by distillation or crystallisation. . ŕ |
| priorityDate | 1997-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.