| abstract |
The present invention relates to compounds of formula (I): wherein R 1, R 2, R 3, R 4 and R 6 are independently hydrogen or C 1-6 alkyl, R 5 is hydrogen, C 1-6 alkyl, or -COR 7; and in the latter formula, R7 is alkyl having 1 to 6 carbon atoms, n is 0 or 1, and X is oxygen or a hydroxyimino group, provided that when n is 0, at least two of R1, R2, R3 and R4 are hydrogen. is different and when n is 1 then R3 and R4 are other than hydrogen. and pharmaceutical compositions containing such compounds. The compounds of the present invention are excellent progestogens without any residual androgen activity. ŕ |