http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-221649-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-824 |
| filingDate | 1998-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d7a6a977fec8222b2528bcc80a48c22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7107d6fd7bd3b14b812470b946b5ce64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_461f3bb9d0ea2c98004f4f6f15bf5860 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e230161c558ad4b97d958b317361142f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_439987cd815c7db5ababd56f853a355c |
| publicationDate | 2002-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-221649-B1 |
| titleOfInvention | Process for the preparation of N- (4-fluorophenyl) -N- (1-methyl-ethyl) -2- [5- (trifluoromethyl) -1,3,4-thiadiazol-2-yl] oxyacetamide \ t using an aromatic solvent |
| abstract | The present invention relates to a process for N- (4-fluorophenyl) -N- (1-methylethyl) -2- [5- (trifluoromethyl) -1,3,4-thiadiazol-2-yl] oxy- to produce acetamide in an aprotic aromatic solvent. In step (a) of the process, 2- (methylsulfonyl) -5- (trifluoromethyl) -1,3,4-thiadiazole N- (4-fluorophenyl) -N- (1-methylethyl) Reacting with 2-hydroxyacetamide and aqueous alkali in the presence of a caprotic aromatic solvent to form an aqueous phase and a monoorganic phase; in step (b) the phases are acidified; in step (c) the phases are separated and in step (d) N- (4-fluorophenyl) -N- (1-methylethyl) -2- [5- (trifluoro) is recovered from the organic phase. (methyl) -1,3,4-thiadiazol-2-yl] oxyacetamide. The aprotic aromatic solvent used in the process is toluene, xylene, cumene or mesitylene. Aqueous alkali metal carbonate solution or aqueous alkali metal hydroxide solution is used as the aqueous alkaline agent. 2- (Methylsulfonyl) -5- (trifluoromethyl) -1,3,4-thiadiazole to N- (4-fluorophenyl) -N- (1-methylethyl) -2-hydroxyacetamide the relative molar ratio is preferably between about 1.5: 1 and about 1: 1.5. ŕ |
| priorityDate | 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.