| abstract |
The present invention relates to a process for the preparation of compounds of formulas I, II and III. In the formulas, m is 1, 2 or 3, R is H, Li, Na, K, Mg or NH 4, R 1 is halogen and R 2 is fluoro, chloro or bromo, C 1-6 alkyl, C 1-6 alkoxy or perfluoro; The C 1-3 alkyl group. The phenoxyphenylsulfonyl halides of the formula I prepared by the process of the present invention are useful as intermediates for the preparation of matrix metalloproteinase inhibitors. Matrix metalloproteinase (MMP) inhibitors are useful in the treatment of various diseases such as arthritis, inflammatory diseases, asthma, Alzheimer's disease, cerebral ischemia, congestive heart failure and the like. ŕ |