| abstract |
FIELD OF THE INVENTION The present invention relates to pharmaceutical compositions containing a allylamine derivative of formula (I) in free base or in acid addition salt form, which are topically applicable to fungal nail diseases. In addition to the allylamine derivative, the compositions of the invention, such as nail polishes, include a film-forming polymer selected from the group consisting of polyvinyl acetate, copolymers of acrylic and methacrylic acid alkyl esters with quaternary ammonium radicals, and methyl vinyl ether. / maleic acid monoalkyl ester copolymerates and, if necessary, additional additives such as plasticizers, film modifiers, surfactants, penetration enhancers, colorants, antioxidants, complexing agents, UV absorbers, water and solvents. The compositions of the present invention have no systemic effect and the active ingredient contained therein is capable of penetrating deeper layers of nail tissue, i.e., fungi in the lower layers. ŕ |