http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-218387-B

Outgoing Links

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-38
filingDate 1995-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a2306af34e96f281338ec6287a36ea2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f46746970998f5f1a8626b9511d6e40d
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publicationDate 2000-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-218387-B
titleOfInvention Process for the preparation of 3-amino-4- (ethoxycarbonyl) pyrazole
abstract The present invention relates to a process for the preparation of 3-amino-4-ethoxycarbonylpyrazole of the formula (I) by hydrazine ring closure of an acetic acid derivative by the reaction of an ethylmethylene cyanoacetic acid ethyl ester of formula (II) at a temperature of between 15 and 25 ° C , in the presence of hydrazine, hydrazine or hydrazine hydrate in the presence of a mineral acid, then the reaction is carried out in the presence of alkali metal hydroxide or alkali metal carbonate at a temperature of 80 ° C to 98 ° C, the reaction mixture is cooled and the resulting (I) is cooled. It is isolated by compounding the formula II. Compound (I) is a valuable pharmaceutical intermediate. ŕ
priorityDate 1995-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 38.