http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-218387-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-38 |
filingDate | 1995-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a2306af34e96f281338ec6287a36ea2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f46746970998f5f1a8626b9511d6e40d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a228b4e396fd61c9b7d132a520f54070 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b1b5abfddec0406c51e4427573cb4dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91de479072aee99aec29c7fe09581147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01fa1229a44228d541a6d091a4e34511 |
publicationDate | 2000-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HU-218387-B |
titleOfInvention | Process for the preparation of 3-amino-4- (ethoxycarbonyl) pyrazole |
abstract | The present invention relates to a process for the preparation of 3-amino-4-ethoxycarbonylpyrazole of the formula (I) by hydrazine ring closure of an acetic acid derivative by the reaction of an ethylmethylene cyanoacetic acid ethyl ester of formula (II) at a temperature of between 15 and 25 ° C , in the presence of hydrazine, hydrazine or hydrazine hydrate in the presence of a mineral acid, then the reaction is carried out in the presence of alkali metal hydroxide or alkali metal carbonate at a temperature of 80 ° C to 98 ° C, the reaction mixture is cooled and the resulting (I) is cooled. It is isolated by compounding the formula II. Compound (I) is a valuable pharmaceutical intermediate. ŕ |
priorityDate | 1995-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.