http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-213386-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5a95d4999542f2d9fa147bfed0e90cf
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-20
filingDate 1992-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66b0e7c2449302e7c79c1c84d7848724
publicationDate 1997-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-213386-B
titleOfInvention Process for the preparation of ethyl-6-(formyl-oxy)- and ethyl-6-(trichloroacetimidoyl-oxy)-4-hexenoate
abstract The present invention relates to a process for the preparation of ethyl 6- (formyloxy) -4-hexenoate and ethyl 6- (trichloroacetimidyloxy) -4-hexenoate. According to the invention, they are dehydrated and formylated during the thermal reaction in the presence of erythritol formic acid; the 4- (formyloxy) -3-hydroxy-1-butene obtained is reacted with triethyl orthoacetate under thermal reaction conditions and the resulting ethyl 6- (formyloxy) -4-hexenoate is prepared; and optionally converting into ethyl 6-hydroxy-4-hexenoate in the presence of ethanol and hydrochloric acid; by reacting it with trichloroacetonitrile to form ethyl 6- (trichloroacetimidyloxy) -4-hexenoate; and, if desired, converting the acid into a pharmaceutically acceptable salt. EN 213 386 B Scope of the description: 5 pages (including 2 sheets)
priorityDate 1991-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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