| abstract |
Described are N-Benzopyranyllactame of formula I. in which R¹ is CN, NO₂, SO n -Ar, stands; where n = 1 or 2, Ar is an aromatic or heteroaromatic system which is unsubstituted or substituted and p is 1 or 2, R² is H, OH, (C₁-C₂) alkoxy, (C₁-C₂) alkyl, halogen or NR⁵R⁶ wherein R⁵ and R⁶ are the same or different and are H, (C₁-C₂) alkyl or (C₁-C₂ ) Alkylcarbonyl, R³ and R⁴ are the same or different and are alkyl having 1-4 C atoms, the above meanings of R¹ and R² can also be reversed, X is a chain (CH₂) m which is substituted by at least 1 and at most 2m-1 (C₁-C₂) alkyl groups, as well as by a heteroatom Y in the meaning of O, NR⁷, S may be interrupted and R⁷ is H or (C₁-C₄) alkyl and m is 2, 3 or 4.n n n They have antihypertensive activity and / or ureter relaxant activity.n n n Also described is their production, their use; Also, pharmaceutical preparations are described on their basis. |