http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-205382-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_035973eaea4c1326a45a871b56df95db |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6459 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 |
| filingDate | 1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7665e761ae4bf446034aa6e935d1badd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a47ab98c3acb4d38a88385ceedbebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a950de6a134e9913e37b20688d75a31c |
| publicationDate | 1992-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-205382-B |
| titleOfInvention | Process for producin tissular plasminogen activator from cells cultured in lectin-containing nutrient medium |
| abstract | Increased yields of enzymes, particularly tissue plasminogen activator (tPA), are produced from cells, particularly CNCM I-222 cells, by a process using less concentrated lectin, particularly concanavalin A, in culture medium added to replace initial growth medium than has been used hitherto. After first harvesting of enzyme in supernatants, the culture can be reactivated by the addition of fresh culture medium containing an even lower lectin concentration, and a further harvest of enzyme obtained. The two harvests of enzyme together can give a greater overall yield than a single harvest after a single induction step employing the conventionally used higher lectin concentration. Enzyme yield can be further increased by repeating the last incubation step once or twice to obtain one or two further harvests. |
| priorityDate | 1987-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.