http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-203741-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 |
| filingDate | 1988-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2eb24cb758b670fc373dcb41dfdfc9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797ba9141f64f3aef34f3bbff6474348 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50951aa9c081cef6893888dcf958587b |
| publicationDate | 1991-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-203741-B |
| titleOfInvention | New process for producing halogeno-1,5-benzothiazepine derivatives |
| abstract | The present invention relates to a novel process for the preparation of 1,5-benzothiazepine derivatives of the formula (I) or their pharmaceutically acceptable acid addition salts, wherein R 1 is lower alkoxy, R 2 is hydrogen or lower alkanoyl, R 3 and R 4 \ t one of the substituents is halogen and the other is hydrogen, R5 and R6 are lower alkyl such that a compound of formula II wherein R1, R2, R3 and R4 are as defined above and X1 is a reactive group; with an amine of formula (I) or a salt thereof, wherein R5 and R6 are as defined above, or a compound of formula (VJ), wherein R1, R2, R3 and R4 are as defined above; in which R5 and R6 are as defined above and Z is as defined above. hydrogen, lower alkyl sulfonyl, arylsulfonyl or sulfo, and optionally converting the resulting compound of formula (I) into a pharmaceutically acceptable acid addition salt thereof. EN 203 741 Scope of the description: 6 pages, figure 2 -1- |
| priorityDate | 1987-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.