| abstract |
Covers oxindole intermediates, and their preparation, of the formula:n wherein X and Y are certain stated substituents or may when taken together form certain ring structures, and R is H or -COR 1 where R 1 is alkyl, cycloalkyl, cycloalkenyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalkyl, (thiophenoxy)alkyl, naphthyl, bicyclo[2.2.1]heptan-2-yl, bicyclo[2.2.1]hept-5-en-2-yl or -(CH 2 ) n -Q-R' where n is 0, 1 or 2, Q is a divalent radical which is a specified heterocycle, and R° is H or alkyl; and also covers the hydrolysis of the compounds (II) to end products of the formula: |