| abstract |
The oxazolidines of the formula <IMAGE> I wherein n signifies the number 1 or 2, T signifies lower carbalkoxy, X signifies phenoxymethyl optionally mono-fluorinated or mono-chlorinated in the ortho-position or phenyl optionally monosubstituted by fluorine, chlorine, trifluoromethyl or lower-alkoxy, Y signifies hydrogen or methyl, and Z signifies a phenyl or thienyl residue substituted in a defined manner, and the physiologically compatible salts thereof have catabolic activity and can be used for the treatment of obesity and diabetes mellitus or for the treatment of conditions which are associated with an increased protein breakdown, or as feed additives for fattening animals. They are manufactured starting from corresponding primary amines. |