| abstract |
Compounds of the formula (I):-n and salts thereof, wherein R' is hydrogen, C 1-6 alkyl, halo, cyano, nitro, amino, a group -NHCOR 4 , a group -COR 5 , or a group -NHC(NCN)NHR 6 ; wherein R 4 is hydrogen, C 1-6 alkoxy, C 1-6 alkyl optionally substituted by phenyl, or R 4 is a group NR 7 R 8 wherein R 7 and R 8 are independently hydrogen, C 1-6 salkyl or benzyl; R 5 is hydroxy, hydrogen, C 1-6 alkyl, C 1-6 alkoxy, or a group -NR 7 R 8 ; and R 6 is hydrogen or C 1-6 alkyl; R 2 is hydrogen or C 1-4 alkyl; R 3 is hydrogen or C 1-4 alkyl; and n is one, and when R 3 is hydrogen n can also be two. n Processes and intermediates for their preparation are described. Pharmaceutical compositions containing them are described, as is their use as inotropic agents. |